AI-powered Drug Development

We create innovative solutions for efficient and rapid drug development using artificial intelligence.

Ligand Pro – is a Russian company specializing in early drug development

Year of foundation

using computational methods. We create digital tools aimed at accelerating the development of promising drug candidates. In collaboration with research groups, pharmaceutical companies, and startups, we validate the effectiveness of our approaches in real drug development pipelines.

2023

Supported by

Postgres Professional

Generation of Small Molecules

De novo generation of candidate molecules with optimal property profiles. Generating molecules from desired structural fragments or for a specified binding site.

Assessment of Small Molecule Interactions with Therapeutic Targets

Predicting the three-dimensional structure and binding affinity of ligand-protein complexes. Selecting high-affinity hits from compound libraries.

Optimization of Therapeutic and Diagnostic Protein Properties

Enhancing stability, improving affinity, and optimizing other parameters of proteins.

Prediction of Small Molecule Properties

Forecasting ADME-Tox profile parameters.

Our mission — efficient development of the drugs of the future using artificial intelligence.

Drug development is a lengthy process that demands significant resources. Even with the most advanced digital technologies, drug development often relies on trial and error, with no guarantee of success. We envision a future where artificial intelligence technologies can significantly reduce the time required to develop new medications.

Ligand Pro is an ambitious interdisciplinary team. We specialize in deep learning,

molecular modeling, and computational methods in chemistry and biology, applying these techniques to address various drug design challenges.

We collaborate with leading organizations and institutions. Together we achieve real change and success.

The Ligand Pro startup was created with the support of Postgres Professional, a Russian developer of the Postgres Pro database management system based on PostgreSQL. Postgres Professional was founded in 2015 by Oleg Bartunov and Teodor Sigaev, PostgreSQL Major Contributors, along with partners Ivan Panchenko and Andrey Fleyta.

Today, the company is one of the world’s leading vendors contributing to PostgreSQL. Postgres Professional employees are the primary developers of full-text search, JSONB, GiST, SP-GiST and GIN indexes. The team also makes contributions to B-Tree indexes and many other PostgreSQL features.

Most of the team comprises representatives from Skoltech, including students, alumni, research staff, and professors.

Skoltech is an international technological university of a new type. Combining world-class education with state-of-the-art research and applied technologies, it nurtures a new generation of technological leaders for high-tech industries. Skoltech has twice been listed among the world’s top 100 young universities according to the prestigious Nature Index ranking. The language of instruction is English